Full-Field Optical Coherence Microscopy
نویسنده
چکیده
Optical coherence tomography (OCT) is a well-established optical imaging technique with micrometer-scale resolution. OCT is based on low-coherence interferometry to measure the amplitude of light backscattered by the sample being imaged [1-4]. The most significant impact of OCT is in ophthalmology for in situ examination of the pathologic changes of the retina [5-8] and measurement of the dimensions of the anterior chamber of the eye [9, 10]. OCT has also been established in a variety of other biomedical applications [11] and for material characterization [12, 13].
منابع مشابه
Partially coherent illumination in full-field interferometric synthetic aperture microscopy.
A model is developed for optical coherence tomography and interferometric synthetic aperture microscopy (ISAM) systems employing full-field frequency-scanned illumination with partial spatial coherence. This model is used to derive efficient ISAM inverse scattering algorithms that give diffraction-limited resolution in regions typically regarded as out of focus. Partial spatial coherence of the...
متن کاملSpectroscopic polarization-sensitive full-field optical coherence microscopy
Full-field optical coherence tomography (FF-OCT) is a recent optical imaging technology based on low-coherence interference microscopy for imaging of semi-transparent samples with ~1 μm spatial resolution. FF-OCT produces en-face tomographic images obtained by arithmetic combination of interferometric images acquired by an array camera. In this paper, we demonstrate a unique multimodal FF-OCT s...
متن کاملFull-color three-dimensional microscopy by wide-field optical coherence tomography.
We demonstrate a method of optical tomography for surface and sub-surface imaging of biological tissues, based on the principle of wide field optical coherence tomography and capable of providing full-color three-dimensional views of a tissue structure. Contour or tomographic images are obtained with an interferometric imaging system using broadband light sources. The interferometric images are...
متن کاملFourier spectrum analysis of full-field optical coherence tomography for tissue imaging
Quantifying structural features and their changes of live intact cells and tissues in three dimensions at micrometre or submicrometre levels is very helpful for accurate disease diagnosis at the early phase. Thus, several quantitative measures of tissue structures have been proposed which may be divided into two categories: one is geometrical or morphological measures such as layer thickness, t...
متن کاملSimultaneous optically sectioned fluorescence and optical coherence microscopy with full-field illumination.
Full-field optical coherence microscopy (FF-OCM) and optically sectioned fluorescence microscopy are two imaging techniques that are implemented here in a novel dual modality instrument. The two imaging modalities use a broad field illumination to acquire the entire field of view without raster scanning. Optical sectioning is achie...
متن کاملDual-modality fluorescence and full-field optical coherence microscopy for biomedical imaging applications
Full-field optical coherence microscopy (FFOCM) is a high-resolution interferometric technique that is particularly attractive for biomedical imaging. Here we show that combining it with structured illumination fluorescence microscopy on one platform can increase its versatility since it enables co-localized registration of optically sectioned reflectance and fluorescence images. To demonstrate...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2012